May 2026 Current Abstracts

Current Abstracts — May 2026
Monthly tobacco research digest  ·  Ontario Tobacco Research Unit
114
Articles
5
Reviews
5
Canadian
60
Open Access
28
In the News
📰 In the News — covered by news or Reddit🔓 Open Access — free full text🍁 Canadian — Canadian author or institutionSR — systematic review / meta-analysis
Generated 2026-05-26  · 
🔥 Hot Topic
Evans-Polce Rebecca J, Lim Chaewon, Smith Danielle M et al.. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2026 May.
# Spotlight Summary

Youth vaping patterns are more complex than simple e-cigarette use—many young people transition between vaping alone, dual use with cigarettes, and quitting altogether. Using longitudinal data from the PATH Study, researchers tracked how frequently youth used nicotine products and measured actual nicotine exposure through biomarkers to understand who develops dependence and continues use over time. These findings help public health practitioners identify which young vapers are at highest risk of sustained nicotine addiction and tobacco product transitions. Understanding these patterns is critical for designing targeted interventions and anticipating whether e-cigarette use serves as a pathway to traditional tobacco products or away from them among youth populations.

In the News 28

Research articles from this digest that have been covered by news media or discussed on Reddit.

▶ Browse 28 media-covered articles
Soulakova Julia N, Crockett Lisa J. Addiction science & clinical practice. 2026 May. doi:10.1186/s13722-026-00674-2
Summary
Among adults who smoke cigarettes daily, switching to alternative tobacco products (such as e-cigarettes or other non-combustible products) during quit attempts was not associated with stronger intentions to quit smoking or greater interest in quitting compared to using evidence-based cessation aids like nicotine replacement therapy. This finding suggests that using alternative tobacco products as a substitution strategy may not enhance motivation or commitment to achieving long-term smoking cessation.
Nebbioso Marcella, Calzolaio Francesca, Castellani Valentina et al.. Toxicology mechanisms and methods. 2026 May. doi:10.1080/15376516.2026.2678476
Summary
Researchers examined whether heated tobacco products (HTPs)—devices that heat rather than burn tobacco—affect blood flow in the eye's choriocapillaris, a layer of tiny blood vessels critical for vision. The study compared smokers who had never used HTPs to understand how these newer tobacco products might impact vascular health, contributing to the limited evidence base on HTP safety.
Heo Geon, Kim Doyoon, Kim Yehyun et al.. JMIR public health and surveillance. 2026 May. doi:10.2196/87537
Summary
Researchers examined how tobacco companies in South Korea use flavor cues and visual design elements on cigarette and heated tobacco product packaging to attract consumers, taking advantage of the country's lack of plain packaging requirements. The study found that packaging remains a significant marketing tool, with flavor descriptors and appealing imagery prominently featured to enhance product appeal and influence purchasing decisions.
Yan Xiao, Liao Chenyi, Qian Shuangqiang et al.. International journal of women's health. 2026. doi:10.1007/s13167-021-00241-6
Summary
Researchers examined breast cancer burden in BRICS countries (Brazil, Russia, India, China, South Africa) from 1990-2021 and investigated whether smoking, high alcohol use, high body mass index, and low physical activity actually cause breast cancer using advanced statistical methods. The study combines population-level disease data with causal analysis to explain differences in breast cancer rates across these countries and identify which risk factors have the strongest causal relationships with breast cancer development.
Arp Stine, Stapelfeldt Christina M, Bast Lotus S. Tobacco prevention & cessation. 2026. doi:10.1177/14034948211047778
Summary
Danish youth aged 15-29 who use cigarettes, e-cigarettes, or smokeless nicotine products report wanting to quit or have attempted to quit at increasing rates. Understanding the specific reasons youth want to quit different nicotine products can help tailor cessation services and support programs more effectively for this age group.
Andersson Johanna, Hansson Malin, Ericson Mia et al.. Tobacco use insights. 2026. doi:10.1001/archpsyc.60.7.692
Summary
Swedish researchers investigated whether tobacco-free nicotine (TFN) products, which are increasingly used by adolescents and often perceived as safer alternatives, are associated with anxiety and depression symptoms, with analysis examining differences between genders. This research addresses a critical gap in understanding the mental health impacts of non-combustible nicotine products among young people as their use continues to rise.
Ruleman Ashlynn M, Mantey Dale S, Sokolovsky Alexander W et al.. Drug and alcohol dependence. 2026 May. doi:10.1016/j.drugalcdep.2026.113197
Summary
Researchers tracked how young people's use of nicotine and tobacco products relates to changes in their alcohol consumption patterns over time. Using data from over 2,600 adolescents and young adults followed over three years, the study applied statistical modeling to identify which tobacco/nicotine product use patterns predict transitions between different levels of alcohol use, helping to understand the interconnected nature of these substance use behaviors.
Johnstone Samantha, Schenkel Ashley, Canazzi Samantha et al.. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2026 May. doi:10.1093/ntr/ntag118
Summary
A systematic review and meta-analysis examined birth outcomes in pregnancies exposed to electronic nicotine delivery systems (e-cigarettes/vaping). Despite ENDS being promoted for smoking cessation during pregnancy, this review synthesizes evidence on their actual effects on newborn health outcomes to clarify whether they represent a safer alternative to conventional cigarettes for pregnant individuals.
Hutson William D, Kasson Erin, Conn Brandon S et al.. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2026 May. doi:10.1093/ntr/ntag120
Summary
Researchers analyzed how nicotine pouches are marketed and presented on YouTube Shorts, examining the types of messaging, imagery, and health-related claims used to promote these products. The findings highlight how social media platforms are being used to market nicotine pouches—often with messaging that portrays them as safer alternatives—raising concerns about how these understudied products are being promoted to potentially young audiences online.
Pokhrel Pallav, Phillips Kristina T, Kawamoto Crissy T et al.. Drug and alcohol dependence. 2026 May. doi:10.1016/j.drugalcdep.2026.113199
Summary
This study examined why adults who smoke cigarettes and use e-cigarettes are turning to oral nicotine pouches, looking beyond just cessation as a motivation. Understanding the various reasons people use these products—such as convenience, social factors, or addiction management—can help public health professionals better understand the landscape of nicotine product use among dual users.
Yang Shasha, Dai Ziyu, Yang Baishuang et al.. Ecotoxicology and environmental safety. 2026 May. doi:10.1016/j.ecoenv.2026.120288
Summary
Cigarette smoke damages the cells lining blood vessels in the lungs, creating an environment that promotes the spread of lung adenocarcinoma tumors. The study identified a specific molecular pathway (BMP4-Smad1/5/9-ID1 axis) through which smoke-induced vascular damage facilitates cancer metastasis, suggesting that smoking's harmful effects extend beyond direct damage to cancer cells themselves to reshape the surrounding tissue environment in ways that accelerate cancer progression.
Collin Camille, Perney Pascal, Jeanjean Luc et al.. Annales d'endocrinologie. 2026 May. doi:10.1016/j.ando.2026.102578
Summary
This retrospective study of 78 patients examined smoking status and cessation management in people with moderate to severe Graves' orbitopathy, an eye condition associated with thyroid disease. The research highlights smoking as a significant modifiable risk factor for this condition and documents how smoking cessation is being managed in clinical practice for patients with this eye disease.
Dar Reuven, Ruppin Shachar. Current neuropharmacology. 2026 May. doi:10.2174/011570159X454604260429065421
SR
Summary
A meta-analysis of laboratory studies examined whether nicotine alone—without the sensory cues and contextual factors associated with smoking tobacco—acts as a reinforcer that keeps smokers dependent. The findings clarify the extent to which isolated nicotine, compared to the full tobacco smoking experience, drives continued smoking behaviour and nicotine dependence.
Derefinka Aleksandra, Słowik Joanna, Ćwirko Hanna et al.. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2026 May. doi:10.1016/j.fct.2026.116165
Summary
This research examines heavy metal contamination in traditional cigarettes and newer nicotine products, identifying potential toxic exposure sources. The findings highlight that while novel nicotine products are often marketed as safer alternatives, they may still pose health risks through heavy metal content, raising important questions about the actual safety profile of these emerging products compared to conventional cigarettes.
Brath Helmut, Huber Simone, Parzer Verena et al.. Wiener klinische Wochenschrift. 2026 May. doi:10.1016/j.vaccine.2017.07.064
Summary
Smoking and secondhand smoke exposure significantly increase both the development of diabetes and the risk of serious diabetes complications. While quitting smoking may lead to some weight gain and temporary increase in diabetes risk, the cardiovascular and overall health benefits of cessation substantially outweigh these concerns, resulting in reduced heart disease and premature death.
Hatsukami Dorothy, Jensen Joni, Reisinger Sarah et al.. Tobacco control. 2026 May. doi:10.1136/tc-2025-059771
Summary
A randomised clinical trial examined how banning ventilated cigarette filters—which create the false impression of reduced harm—might affect smoking behaviour and exposure to toxic smoke chemicals. The study compared smoking patterns and biomarkers of smoke exposure between people who smoked unventilated versus ventilated filtered cigarettes to inform potential regulatory decisions about filter ventilation.
Han Dae-Hee, Martines Paul W, Duran Charlotte et al.. Addiction (Abingdon, England). 2026 May. doi:10.1111/add.70475
Summary
Researchers tested how different nicotine concentrations and pH levels in oral nicotine pouches affect their appeal and sensory experience among users. The study's findings on product characteristics will help inform evidence-based regulatory approaches to address nicotine pouch use, particularly among young people.
Poonphol Prasittichai, Lueamsingkhon Pharanyou, Thongsutt Tiwaphon et al.. Tobacco prevention & cessation. 2026. doi:10.2105/AJPH.2021.306416
Summary
A cross-sectional study examined e-cigarette use prevalence and assessed knowledge and attitudes toward e-cigarettes among university undergraduate students, comparing health science and non-health science majors. The research addresses growing public health concerns about the increasing popularity of e-cigarettes among young adults in higher education settings.
Hagen L, Kazi G N. Public health action. 2026 May. doi:10.1136/tc-2024-059219
🍁 Canadian 🔓 Open Access
Summary
Tobacco and vaping companies continue to develop innovative products and marketing strategies to recruit new customers and maintain market share across generations. The research highlights how the industry targets emerging consumer segments through novel products and promotional schemes, contributing to sustained nicotine dependence in new populations.
Rossi Kristen R, Russell Scott J, Mabila Sithembile L. MSMR. 2026 May.
Summary
Researchers assessed tobacco and nicotine use among active U.S. military service members in 2023 by combining health assessment data with medical diagnostic codes to address the challenge of accurately measuring smoking patterns in this population. The study highlights the importance of using multiple data sources to capture tobacco use prevalence among military personnel, a group at elevated risk for smoking-related health consequences.
Yoshihara Shota, Takahashi Kayoko, Uemura Chiaki et al.. Journal of medical Internet research. 2026 May. doi:10.1080/14622200210123581
Summary
A Japanese workplace smoking cessation program combined nicotine replacement therapy (gum or patches) with a group-based digital peer-support app to help workers quit smoking. The program achieved high cessation success rates, suggesting that integrating pharmacotherapy with digital peer support platforms may be an effective strategy for improving smoking cessation outcomes in occupational health settings.
Reddit: r/stopsmoking (↑2 / 7 comments)  ·  r/stopsmoking (↑1 / 6 comments)  ·  r/stopsmoking (↑3 / 1 comments)
Silva Júnior João Ferreira, Gonçalves Filho Antônio, Carneiro Verônica Silva. Cadernos de saude publica. 2026. doi:10.1101/2025.02.14.25322276v1
Summary
A Brazilian national survey tracked electronic nicotine delivery systems (ENDS) use between 2019 and 2023 to understand how common vaping is and who uses these products. The research found that ENDS use has been increasing in Brazil despite the country's strong tobacco control policies, with important variations across different population groups that public health programs should consider.
Manzour Ayat F, Eldin Waleed Salah, Mossad Isis M et al.. The Journal of the Egyptian Public Health Association. 2026 May. doi:10.4103/ejcdt.ejcdt_37_18
Summary
Healthcare providers in Egyptian maternity hospitals face significant barriers to delivering smoking cessation counseling to pregnant patients, despite understanding tobacco's risks during pregnancy. The study identified time constraints as a major obstacle preventing consistent implementation of cessation interventions in this critical clinical setting.
Yang Meng, Lohrmann David K, Huang Chunfeng et al.. Substance use & misuse. 2026 May. doi:10.1080/10826084.2026.2673411
Summary
Research examined the progression from wanting to quit e-cigarettes through actual quit attempts and sustained abstinence among U.S. adults. The study addresses a gap in understanding the complete pathway of e-cigarette cessation, moving beyond simply measuring how many people express interest in quitting to explore whether those intentions translate into actual behavior change.
Reddit: r/stopsmoking (↑9 / 5 comments)
Durazzo Timothy C, Carolan Riley E, Beauregard Lauren H et al.. Drug and alcohol dependence. 2026 May. doi:10.1016/j.drugalcdep.2026.113194
Summary
Researchers examined brain metabolite levels in people receiving treatment for alcohol use disorder, comparing those who smoke cigarettes to non-smokers. Cigarette smoking, along with a history of major depression and PTSD diagnosis, were associated with altered metabolite levels in a brain region (left dorsolateral prefrontal cortex) important for decision-making and impulse control, suggesting smoking may have additional neurobiological effects in this vulnerable population.
Evans-Polce Rebecca J, Lim Chaewon, Smith Danielle M et al.. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2026 May. doi:10.1093/ntr/ntag108
Summary
This research examined how US youth transition between different nicotine use patterns (vaping only, dual use with cigarettes, or switching away from vaping) and whether these transitions relate to how often they use e-cigarettes, their level of nicotine dependence, and measurable nicotine exposure in their bodies. Understanding these usage patterns and dependencies can help public health practitioners identify youth at highest risk for sustained nicotine addiction and inform targeted intervention strategies.
Jamaludin Siti Anisah, Abdul-Razak Suraya, Nik-Mohd-Nasir Nik Munirah et al.. Digital health. 2026. doi:10.1186/s40814-022-01002-6
Summary
Researchers conducted usability and utility testing of FrESH, a web-based application designed to help adolescents quit tobacco and e-cigarette use. The study evaluated how well the app worked and whether it was practical and user-friendly for young people trying to quit nicotine products.
Sun Ruoyan, Benowitz Neal L, Hammond David et al.. American journal of preventive medicine. 2026 May. doi:10.1016/j.amepre.2026.108421
🍁 Canadian
Summary
Young adults who both vape and smoke cannabis experience higher rates of respiratory symptoms compared to those using only one method or neither. Using data from a large national study of 5,211 young adults aged 18-24 without prior respiratory issues, researchers found that dual use of cannabis vaping and smoking significantly increased the risk of developing new respiratory symptoms over time.
Reviews & Meta-Analyses 5
▶ Browse 5 reviews
Cessation—Pharmacotherapy
Dar Reuven, Ruppin Shachar. Current neuropharmacology. 2026 May. doi:10.2174/011570159X454604260429065421
Summary
A meta-analysis of laboratory studies examined whether nicotine alone—without the sensory cues and contextual factors associated with smoking tobacco—acts as a reinforcer that keeps smokers dependent. The findings clarify the extent to which isolated nicotine, compared to the full tobacco smoking experience, drives continued smoking behaviour and nicotine dependence.
E-cigarettes—Health Effects
Jurado-Hernández Jenny, Álvarez-Orozco Iván, Salvador-Oscco Edison et al.. BMC pulmonary medicine. 2026 May. doi:10.1186/s12890-026-04349-1
Summary
A systematic review and meta-analysis examined the clinical presentation, imaging characteristics, and outcomes of patients with e-cigarette or vaping product use-associated lung injury (EVALI). This comprehensive analysis synthesizes evidence on how EVALI manifests in patients, what radiological patterns are observed, and mortality rates associated with this condition.
E-cigarettes—Youth/Adolescents
Akca Sumengen Aylin, Adekeye Olayemi T, Cakir Gokce N et al.. Frontiers in psychiatry. 2026. doi:10.1177/15248399221100793
Summary
A systematic review and meta-analysis examined how effective vaping prevention campaign messages are at changing what young people think and do about vaping. The research synthesized evidence on whether public health campaigns designed to prevent vaping actually work to reduce vaping intentions and use among adolescents and young adults, addressing a gap in knowledge about campaign effectiveness for this population.
Health Effects—Cancer
Aswathi G, Carvalho Andre, Palaniraja Sathishrajaa et al.. BMC public health. 2026 May. doi:10.1186/s12889-026-27796-1
Summary
A systematic review and meta-analysis examined how smoking tobacco and alcohol consumption increase oral cancer risk at different exposure levels. The research quantifies the dose-response relationships for these established risk factors, providing clearer evidence on how much tobacco and alcohol exposure corresponds to increased cancer risk. These findings can inform public health messaging and clinical guidance about the combined dangers of tobacco and alcohol use for oral health.
Health Effects—Pregnancy/Perinatal
Johnstone Samantha, Schenkel Ashley, Canazzi Samantha et al.. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2026 May. doi:10.1093/ntr/ntag118
Summary
A systematic review and meta-analysis examined birth outcomes in pregnancies exposed to electronic nicotine delivery systems (e-cigarettes/vaping). Despite ENDS being promoted for smoking cessation during pregnancy, this review synthesizes evidence on their actual effects on newborn health outcomes to clarify whether they represent a safer alternative to conventional cigarettes for pregnant individuals.
🍁 Canadian 5

Articles with Canadian authors or institutional affiliations.

▶ Browse 5 Canadian articles
Cessation—Health Systems
Mahmoodianfard Salma, Rashwan Ayah, Heshmati Javad et al.. CJC open. 2026 May. doi:10.1016/j.cjco.2026.01.003
🍁 Canadian 🔓 Open Access
Summary
A community-based smoking cessation program using the Ottawa Model was evaluated during the COVID-19 pandemic to address regional disparities in smoking rates across Canada. The study examined the implementation and effectiveness of this quality improvement approach in a health systems context during a challenging public health period.
E-cigarettes—Products/Marketing
Hagen L, Kazi G N. Public health action. 2026 May. doi:10.1136/tc-2024-059219
🍁 Canadian 🔓 Open Access
Summary
Tobacco and vaping companies continue to develop innovative products and marketing strategies to recruit new customers and maintain market share across generations. The research highlights how the industry targets emerging consumer segments through novel products and promotional schemes, contributing to sustained nicotine dependence in new populations.
Epidemiology—Disparities
Karam David, Haddad Chadia, Sacre Hala et al.. Archives of public health = Archives belges de sante publique. 2026 May. doi:10.1186/s13690-026-01934-y
🍁 Canadian 🔓 Open Access
Summary
Researchers examined whether self-reported smoking rates in Lebanon accurately reflect actual tobacco dependence, particularly among women and youth where social desirability bias may affect honest reporting. The study highlights that perceived smoking prevalence may significantly underestimate actual dependence in culturally sensitive populations, suggesting that public health surveillance and intervention strategies need to account for reporting differences across demographic groups.
Health Effects—Respiratory
Sun Ruoyan, Benowitz Neal L, Hammond David et al.. American journal of preventive medicine. 2026 May. doi:10.1016/j.amepre.2026.108421
🍁 Canadian
Summary
Young adults who both vape and smoke cannabis experience higher rates of respiratory symptoms compared to those using only one method or neither. Using data from a large national study of 5,211 young adults aged 18-24 without prior respiratory issues, researchers found that dual use of cannabis vaping and smoking significantly increased the risk of developing new respiratory symptoms over time.
Indigenous—Tobacco
Rahman Tabassum, Williams Robyn, Davis Katiska et al.. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2026 May. doi:10.1093/ntr/ntag117
🍁 Canadian
Summary
This study examined factors that protect Aboriginal and Torres Strait Islander youth aged 16-24 years from ever starting to smoke, using data from The Next Generation Youth Wellbeing Study. Understanding the characteristics and circumstances of young Indigenous people who never initiate smoking can inform prevention strategies and help explain why smoking rates remain higher in Indigenous communities despite overall declines since 2004.
All Articles by Category 114
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Cessation—Behavioural Interventions
Hendizadeh Aaron N, Wen Amy, Guidi Ryan et al.. Journal of surgical oncology. 2026 May. doi:10.1002/jso.70284
Summary
Breast cancer patients undergoing breast reconstruction surgery may represent a unique population with heightened motivation to quit smoking, as surgical outcomes and recovery can be significantly affected by smoking status. This study examines whether breast reconstruction presents a teachable moment and opportunity for targeted smoking cessation interventions among this patient population.
Rome Mélanie, Laqueille Xavier, Meslot Carine et al.. Contemporary clinical trials communications. 2026 Jun. doi:10.1136/bmj.h1258
Summary
The PRISANTABAC Study is a randomized controlled trial testing a cognitive-behavioral therapy-based smoking cessation intervention in French prisons, where smoking rates exceed 70%. This research addresses a significant gap in evidence-based cessation programs for incarcerated populations, who experience disproportionately high smoking rates and limited access to evidence-based treatment options.
Tonkin Sarah S, Baltazar Ashton R, Love Taylor A et al.. Substance use & misuse. 2026 May. doi:10.1080/10826084.2026.2637153
Summary
Researchers examined how smoking abstinence affects the brain's ability to learn and adapt to changing situations using a probabilistic learning task. The study helps explain why smokers continue smoking despite knowing about negative health consequences, by investigating the cognitive mechanisms underlying difficulty in adjusting behavior when reinforcement patterns change.
Agterberg Silvana, Shuter Jonathan, Stanton Cassandra A et al.. Journal of racial and ethnic health disparities. 2026 May. doi:10.1177/1090198106294652
Summary
This randomized clinical trial examined how experiences of race/ethnicity-based discrimination affect smoking dependence and quit success among Black and Hispanic/Latine people living with HIV. The research highlights the intersection of discrimination and tobacco use in this vulnerable population, providing evidence to inform culturally-tailored smoking cessation interventions that address both addiction and the health impacts of discrimination.
Li Meng Yao, Yiu Yin Ting, Zhao Sheng Zhi et al.. Tobacco induced diseases. 2026. doi:10.1002/14651858.CD000146.pub5
Summary
A pilot trial evaluated whether providing one week of chewing gum could help smokers quit by managing cravings. The study assessed how feasible and acceptable this low-cost self-help strategy was, and whether it showed promise for smoking cessation outcomes.
Whitmore Hannah, Hubbard Erin, Cooper Bruce et al.. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2026 May. doi:10.1093/ntr/ntag110
Summary
A randomized controlled trial evaluated the Parks and Recreation Quit Smoking Program, a group-based smoking cessation intervention designed specifically for adults with serious mental illness, a population with significantly higher smoking rates and related health burden. The study tested whether this behavioural intervention could effectively help people with serious mental illness quit smoking, addressing a critical gap in cessation support for this vulnerable group.
Cessation—Digital/Mobile
Abo-Tabik Maryam, Costen Nicholas, Benn Yael. Scientific reports. 2026 May. doi:10.1109/ACCESS.2024.3468470
Summary
Researchers demonstrated that smartphone movement data collected passively (without active user participation) can reliably predict when smokers are likely to experience cravings or have lapses in their quit attempt. This technology could enable real-time, personalized smoking cessation support by identifying high-risk moments based on a person's location patterns and movements, offering a novel approach to preventing relapse during quit attempts.
Heffner Jaimee L, Baker Kelsey, Fan Xinyi et al.. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2026 May. doi:10.1093/ntr/ntag113
Summary
Researchers tested a new digital smoking cessation program designed specifically for sexual and gender minority young adults, using an avatar-based interface to deliver culturally-tailored support. This randomized controlled pilot trial evaluated whether the intervention was acceptable to users and effective at helping this population quit smoking, addressing a gap in cessation resources for this group that experiences higher smoking rates.
Yoshihara Shota, Takahashi Kayoko, Uemura Chiaki et al.. Journal of medical Internet research. 2026 May. doi:10.1080/14622200210123581
Summary
A Japanese workplace smoking cessation program combined nicotine replacement therapy (gum or patches) with a group-based digital peer-support app to help workers quit smoking. The program achieved high cessation success rates, suggesting that integrating pharmacotherapy with digital peer support platforms may be an effective strategy for improving smoking cessation outcomes in occupational health settings.
Reddit: r/stopsmoking (↑2 / 7 comments)  ·  r/stopsmoking (↑1 / 6 comments)  ·  r/stopsmoking (↑3 / 1 comments)
Martinez Ursula, Vinci Christine, Hernandez Paula et al.. JMIR formative research. 2026 May. doi:10.1016/j.ypmed.2015.10.006
Summary
Researchers conducted formative research to develop the first validated, Spanish-language, culturally tailored smoking cessation mobile app for Spanish speakers in the United States. The study involved gathering input from Hispanic or Latino adults to inform the design and adaptation of a mobile app intervention that addresses the unique needs and preferences of this population, filling a significant gap in available cessation tools.
Tuz Canan, Merder Demet, Unal Bahar Urun et al.. BMC primary care. 2026 May. doi:10.1371/journal.pone.0269674
Summary
Researchers evaluated the quality and reliability of smoking cessation advice generated by artificial intelligence systems for use in primary care patient education. This study addresses an important gap in understanding whether AI tools can provide safe and effective cessation support, particularly for patients in under-resourced settings who may have limited access to traditional smoking cessation programs.
Jamaludin Siti Anisah, Abdul-Razak Suraya, Nik-Mohd-Nasir Nik Munirah et al.. Digital health. 2026. doi:10.1186/s40814-022-01002-6
Summary
Researchers conducted usability and utility testing of FrESH, a web-based application designed to help adolescents quit tobacco and e-cigarette use. The study evaluated how well the app worked and whether it was practical and user-friendly for young people trying to quit nicotine products.
Cessation—Health Systems
Budin Eugenia-Corina, Stoica-Buracinschi Florin, Ianoși Edith Simona et al.. BMC medical education. 2026 May. doi:10.1186/s12909-026-09435-w
Summary
Researchers evaluated medical educators' and students' opinions on using an artificial intelligence-powered virtual patient app to teach brief smoking cessation counseling skills. The study found that this technology-based educational tool shows promise for addressing the gap in smoking cessation training within medical education curricula.
Mahmoodianfard Salma, Rashwan Ayah, Heshmati Javad et al.. CJC open. 2026 May. doi:10.1016/j.cjco.2026.01.003
🍁 Canadian 🔓 Open Access
Summary
A community-based smoking cessation program using the Ottawa Model was evaluated during the COVID-19 pandemic to address regional disparities in smoking rates across Canada. The study examined the implementation and effectiveness of this quality improvement approach in a health systems context during a challenging public health period.
Cessation—Pharmacotherapy
Rubinstein Mark, Rowe David, Perdok Renee et al.. Journal of health economics and outcomes research. 2026. doi:10.1136/bmjopen-2024-091961
Summary
This matching-adjusted indirect comparison evaluated the effectiveness of cytisinicline, a plant-based medication, against varenicline (a commonly prescribed smoking cessation drug) by analyzing data from separate clinical trials. Cytisinicline works by binding to nicotine receptors in the brain to reduce cravings and withdrawal symptoms, offering a potentially new pharmacological option for smokers seeking to quit.
Kusi-Boadum Nana Kofi, Taylor Cynthia M, Shetty Ritu A et al.. Pharmacology, biochemistry, and behavior. 2026 May. doi:10.1016/j.pbb.2026.174213
Summary
Researchers compared how nicotine and varenicline (a smoking cessation medication) affect movement and brain reward responses in animal models to better understand how these substances work. The findings help validate varenicline as an effective tool for detecting nicotine substitutes and antagonists, which could improve the development of future smoking cessation medications.
Dar Reuven, Ruppin Shachar. Current neuropharmacology. 2026 May. doi:10.2174/011570159X454604260429065421
SR
Summary
A meta-analysis of laboratory studies examined whether nicotine alone—without the sensory cues and contextual factors associated with smoking tobacco—acts as a reinforcer that keeps smokers dependent. The findings clarify the extent to which isolated nicotine, compared to the full tobacco smoking experience, drives continued smoking behaviour and nicotine dependence.
McLean Nadia A, Greenway Abigail E, Gray Ty L et al.. Neuropharmacology. 2026 May. doi:10.1016/j.neuropharm.2026.111029
Summary
Researchers investigated how genetic differences in brain nicotinic acetylcholine receptors affect the effectiveness of nicotine and varenicline (a smoking cessation medication) in treating motor problems caused by alcohol withdrawal. The findings suggest that genetic variation in these receptors may influence how well these medications work, which could help explain why some individuals respond better to certain treatments than others.
Sriram Siddarth, Arnolda Leonard. Therapeutic advances in drug safety. 2026. doi:10.1177/20420986261448034
Summary
A case report describes a patient who developed dilated cardiomyopathy (a serious heart condition) while using both semaglutide (a diabetes/weight loss medication) and long-term nicotine replacement therapy (NRT). The case highlights an underexplored concern about potential cardiovascular risks when combining these medications, suggesting that healthcare providers should be aware of this potential interaction when prescribing NRT to patients also taking semaglutide.
Herman Rae J, Caffrey Antonia, Pothikamjorn Austin et al.. Biological psychiatry. 2026 May. doi:10.1016/j.biopsych.2026.05.002
Summary
GLP-1 receptor agonists—a class of medications already used to treat diabetes and obesity—show promise as a potential new medication for treating nicotine and psychostimulant use disorders based on preclinical research and early clinical findings. These drugs may help address the significant treatment gap, as current nicotine cessation medications have limited long-term effectiveness and no approved medications currently exist for psychostimulant use disorder.
Cessation—Pregnancy
Gulley Teresa, Hammer Denise, Jarvill Melissa. Maternal and child health journal. 2026 May. doi:10.1111/j.1365-2648.2005.03621.x
Summary
This integrative review examined how pregnant women perceive and understand the risks of smoking tobacco during pregnancy. The review synthesizes existing literature on pregnant women's knowledge, attitudes, and perceptions regarding smoking risks, which can inform the development of more effective cessation interventions tailored to this vulnerable population.
Manzour Ayat F, Eldin Waleed Salah, Mossad Isis M et al.. The Journal of the Egyptian Public Health Association. 2026 May. doi:10.4103/ejcdt.ejcdt_37_18
Summary
Healthcare providers in Egyptian maternity hospitals face significant barriers to delivering smoking cessation counseling to pregnant patients, despite understanding tobacco's risks during pregnancy. The study identified time constraints as a major obstacle preventing consistent implementation of cessation interventions in this critical clinical setting.
Cessation—Youth
Corsello Antonio, Di Cicco Maria Elisa, Reali Laura et al.. Italian journal of pediatrics. 2026 May. doi:10.1186/s13052-026-02281-y
Summary
Adolescent nicotine dependence is a significant public health concern due to the developing brain's heightened vulnerability to nicotine and the emergence of new tobacco products. Clinically meaningful dependence can develop rapidly in adolescents even with brief and intermittent tobacco use. This position paper addresses evidence-based cessation strategies tailored to address the unique neurobiological and developmental characteristics of adolescent smokers.
Arp Stine, Stapelfeldt Christina M, Bast Lotus S. Tobacco prevention & cessation. 2026. doi:10.1177/14034948211047778
Summary
Danish youth aged 15-29 who use cigarettes, e-cigarettes, or smokeless nicotine products report wanting to quit or have attempted to quit at increasing rates. Understanding the specific reasons youth want to quit different nicotine products can help tailor cessation services and support programs more effectively for this age group.
E-cigarettes—Cessation
Lyu Joanne Chen, White Justin S, Shlipak Kaira et al.. JMIR pediatrics and parenting. 2026 May. doi:10.2196/46283
Summary
Researchers tested a peer-mentored social media intervention to help young people quit vaping, addressing challenges like low engagement that often limit the effectiveness of online cessation programs. The pilot study used peer mentors within social media groups to provide support and encouragement for youth trying to stop e-cigarette use, a strategy designed to improve participant retention and engagement in digital cessation efforts.
Cho Yoo Jin, Hinton Alice, Nshimiyimana Jean et al.. Addiction (Abingdon, England). 2026 May. doi:10.1111/add.70421
Summary
Researchers compared whether higher wattage e-cigarettes (which deliver nicotine more effectively) help smokers completely switch away from combustible cigarettes better than lower wattage e-cigarettes. The study measured both smoking substitution rates and exposure to a harmful carcinogen found in cigarette smoke to determine if complete switching reduces health risks from this specific toxin.
Williams Brian S, Kasza Karin A, Hyland Andrew et al.. Pediatrics. 2026 May. doi:10.1542/peds.2025-075276
Summary
Young adults aged 18-24 who vape most frequently compared to other age groups were examined to identify factors predicting quit attempts and successful cessation from e-cigarettes. Understanding these predictors is important because current evidence on what helps young adults quit vaping is limited, and identifying these factors can inform future cessation interventions for this high-vaping population.
Yang Meng, Lohrmann David K, Huang Chunfeng et al.. Substance use & misuse. 2026 May. doi:10.1080/10826084.2026.2673411
Summary
Research examined the progression from wanting to quit e-cigarettes through actual quit attempts and sustained abstinence among U.S. adults. The study addresses a gap in understanding the complete pathway of e-cigarette cessation, moving beyond simply measuring how many people express interest in quitting to explore whether those intentions translate into actual behavior change.
Reddit: r/stopsmoking (↑9 / 5 comments)
E-cigarettes—Co-use
Soulakova Julia N, Crockett Lisa J. Addiction science & clinical practice. 2026 May. doi:10.1186/s13722-026-00674-2
Summary
Among adults who smoke cigarettes daily, switching to alternative tobacco products (such as e-cigarettes or other non-combustible products) during quit attempts was not associated with stronger intentions to quit smoking or greater interest in quitting compared to using evidence-based cessation aids like nicotine replacement therapy. This finding suggests that using alternative tobacco products as a substitution strategy may not enhance motivation or commitment to achieving long-term smoking cessation.
Ruleman Ashlynn M, Mantey Dale S, Sokolovsky Alexander W et al.. Drug and alcohol dependence. 2026 May. doi:10.1016/j.drugalcdep.2026.113197
Summary
Researchers tracked how young people's use of nicotine and tobacco products relates to changes in their alcohol consumption patterns over time. Using data from over 2,600 adolescents and young adults followed over three years, the study applied statistical modeling to identify which tobacco/nicotine product use patterns predict transitions between different levels of alcohol use, helping to understand the interconnected nature of these substance use behaviors.
Pokhrel Pallav, Phillips Kristina T, Kawamoto Crissy T et al.. Drug and alcohol dependence. 2026 May. doi:10.1016/j.drugalcdep.2026.113199
Summary
This study examined why adults who smoke cigarettes and use e-cigarettes are turning to oral nicotine pouches, looking beyond just cessation as a motivation. Understanding the various reasons people use these products—such as convenience, social factors, or addiction management—can help public health professionals better understand the landscape of nicotine product use among dual users.
Lee Jung Ah, Min Lee Cheol, Cho Hong-Jun. Tobacco induced diseases. 2026. doi:10.1056/EVIDoa2300229
Summary
This cross-sectional study examined nicotine dependence levels among Korean adults who use different combinations of combustible cigarettes, e-cigarettes, and heated-tobacco products. The research reveals how patterns of multi-product tobacco use affect dependence severity, providing insights into the evolving landscape of tobacco consumption beyond traditional cigarette smoking.
E-cigarettes—Health Effects
Derefinka Aleksandra, Słowik Joanna, Ćwirko Hanna et al.. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2026 May. doi:10.1016/j.fct.2026.116165
Summary
This research examines heavy metal contamination in traditional cigarettes and newer nicotine products, identifying potential toxic exposure sources. The findings highlight that while novel nicotine products are often marketed as safer alternatives, they may still pose health risks through heavy metal content, raising important questions about the actual safety profile of these emerging products compared to conventional cigarettes.
Yingst Jessica M, Krebs Nicolle M, Dahal Sitasnu et al.. JAMA network open. 2026 May. doi:10.1016/j.ypmed.2025.108389
Summary
A randomized clinical trial examined toxicant exposure levels in people who switched from conventional cigarettes to pod-based electronic cigarettes with nicotine salt formulations. The research evaluated whether this newer generation of e-cigarettes results in reduced exposure to tobacco-related toxicants compared to continued cigarette smoking.
Charoenwatanasuksom Phakwan, Sae-Lee Chanachai, Thaveeratitham Premtip. Respiratory medicine. 2026 May. doi:10.1016/j.rmed.2026.108881
Summary
Researchers compared lung function outcomes between e-cigarette users and combustible cigarette smokers to better understand the health impacts of e-cigarettes, which are often perceived as safer alternatives. This cross-sectional study provides evidence on the respiratory effects of e-cigarette use relative to traditional smoking, contributing to the public health understanding of e-cigarette harms.
Sewell Leslie, Maykovich Tyler J, Babcock Madeline et al.. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2026 May. doi:10.1093/ntr/ntag109
Summary
Researchers examined how coolant flavoring chemicals used in e-cigarettes affect human cells in the mouth and face, finding that these flavorings amplify the harmful effects of nicotine on cellular health. This finding is particularly concerning given that menthol and other cooling flavors remain popular in e-cigarette products and may increase nicotine's toxic potential beyond what nicotine exposure alone would cause.
Alhabdan Sultan, Alashjaai Abdalkareem, Adebisi Yusuff Adebayo. Internal and emergency medicine. 2026 May. doi:10.3390/ijerph14060647
Summary
This study examined how individuals with chronic obstructive pulmonary disease (COPD) use e-cigarettes, as these products are promoted as harm reduction tools in the UK despite limited understanding of their use patterns in this vulnerable population. The research provides insight into e-cigarette adoption among people with a serious respiratory condition linked to smoking, which is important for understanding both potential benefits and risks in disease management.
Jurado-Hernández Jenny, Álvarez-Orozco Iván, Salvador-Oscco Edison et al.. BMC pulmonary medicine. 2026 May. doi:10.1186/s12890-026-04349-1
Summary
A systematic review and meta-analysis examined the clinical presentation, imaging characteristics, and outcomes of patients with e-cigarette or vaping product use-associated lung injury (EVALI). This comprehensive analysis synthesizes evidence on how EVALI manifests in patients, what radiological patterns are observed, and mortality rates associated with this condition.
E-cigarettes—Products/Marketing
Hutson William D, Kasson Erin, Conn Brandon S et al.. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2026 May. doi:10.1093/ntr/ntag120
Summary
Researchers analyzed how nicotine pouches are marketed and presented on YouTube Shorts, examining the types of messaging, imagery, and health-related claims used to promote these products. The findings highlight how social media platforms are being used to market nicotine pouches—often with messaging that portrays them as safer alternatives—raising concerns about how these understudied products are being promoted to potentially young audiences online.
Pankow Wulf, Effertz Tobias. Pneumologie (Stuttgart, Germany). 2026 May. doi:10.1055/a-2867-9991
Summary
The tobacco industry is launching new nicotine products (e-cigarettes, heated tobacco) to offset declining sales of conventional cigarettes and maintain revenue. This research examines how these emerging products may shape future prevalence patterns and what prevention strategies public health should consider in response to aggressive industry marketing of these alternatives.
Barker Hannah E, Brown Jennifer L, Hartmuller Reiley et al.. Tobacco control. 2026 May. doi:10.1136/tc-2026-060081
Summary
Researchers analyzed e-cigarette packaging in Indonesia to identify marketing appeals and design features used on these products. The study found that e-cigarette packaging commonly employs youthful, fun, and flavorful messaging and design elements, which is particularly concerning given that 14.4% of Indonesian youth already use e-cigarettes and exposure to tobacco marketing is linked to increased product use among young people.
Han Dae-Hee, Martines Paul W, Duran Charlotte et al.. Addiction (Abingdon, England). 2026 May. doi:10.1111/add.70475
Summary
Researchers tested how different nicotine concentrations and pH levels in oral nicotine pouches affect their appeal and sensory experience among users. The study's findings on product characteristics will help inform evidence-based regulatory approaches to address nicotine pouch use, particularly among young people.
Wang Tong, Wang Chao, Yang Jing et al.. Frontiers in plant science. 2026. doi:10.16472/j.Chinatobacco.2023.192
Summary
Researchers investigated how aroma components in tobacco leaves and smoke characteristics affect the sensory quality of heated tobacco products (HTPs). Understanding these relationships could inform product development and regulation of HTPs, which are increasingly marketed as alternatives to traditional cigarettes.
Hagen L, Kazi G N. Public health action. 2026 May. doi:10.1136/tc-2024-059219
🍁 Canadian 🔓 Open Access
Summary
Tobacco and vaping companies continue to develop innovative products and marketing strategies to recruit new customers and maintain market share across generations. The research highlights how the industry targets emerging consumer segments through novel products and promotional schemes, contributing to sustained nicotine dependence in new populations.
Kang Naeun, Kang Heewon, Cho Sung-Il et al.. Tobacco induced diseases. 2026. doi:10.1136/tc-2022-057348
Summary
Social media marketing exposure and engagement with e-cigarette content influences youth use through changes in how they perceive the relative harms of e-cigarettes compared to traditional cigarettes. The study found that active engagement with e-cigarette marketing on social media platforms leads users to view e-cigarettes as less harmful, which in turn increases the likelihood of e-cigarette use.
E-cigarettes—Youth/Adolescents
Andersson Johanna, Hansson Malin, Ericson Mia et al.. Tobacco use insights. 2026. doi:10.1001/archpsyc.60.7.692
Summary
Swedish researchers investigated whether tobacco-free nicotine (TFN) products, which are increasingly used by adolescents and often perceived as safer alternatives, are associated with anxiety and depression symptoms, with analysis examining differences between genders. This research addresses a critical gap in understanding the mental health impacts of non-combustible nicotine products among young people as their use continues to rise.
Lim Kuang Hock, Cheong Yoon Ling, Lim Kuang Kuay et al.. Tobacco induced diseases. 2026. doi:10.1136/tc-2023-058011
Summary
This cross-sectional study examined where Malaysian school-going adolescents obtain electronic cigarettes, using data from the 2022 National Health and Morbidity Survey. Understanding the sources of e-cigarette acquisition among youth is essential for developing effective access restriction strategies to reduce adolescent e-cigarette use, which has increased substantially while traditional smoking rates have declined.
Li Jiaxin, Lim Carmen C W, Lee Yan Yee et al.. Tobacco control. 2026 May. doi:10.1136/tc-2025-059905
Summary
Researchers examined 24 vaping education campaigns launched in Australia to determine whether their messaging and strategies align with evidence-based practices for reducing youth vaping. The study found that understanding the content and approach of these campaigns is critical for evaluating their effectiveness and informing future public health efforts, as robust evaluation data on these campaigns remains limited.
Poonphol Prasittichai, Lueamsingkhon Pharanyou, Thongsutt Tiwaphon et al.. Tobacco prevention & cessation. 2026. doi:10.2105/AJPH.2021.306416
Summary
A cross-sectional study examined e-cigarette use prevalence and assessed knowledge and attitudes toward e-cigarettes among university undergraduate students, comparing health science and non-health science majors. The research addresses growing public health concerns about the increasing popularity of e-cigarettes among young adults in higher education settings.
Akca Sumengen Aylin, Adekeye Olayemi T, Cakir Gokce N et al.. Frontiers in psychiatry. 2026. doi:10.1177/15248399221100793
SR
Summary
A systematic review and meta-analysis examined how effective vaping prevention campaign messages are at changing what young people think and do about vaping. The research synthesized evidence on whether public health campaigns designed to prevent vaping actually work to reduce vaping intentions and use among adolescents and young adults, addressing a gap in knowledge about campaign effectiveness for this population.
Baker Yasmin, Warnapala Maneth, Wasan Devan et al.. BMC primary care. 2026 May. doi:10.1186/s12875-026-03350-1
Summary
Primary care professionals play a critical role in addressing youth vaping, yet their current practices, attitudes, and readiness to intervene remain inadequately understood. This systematic review synthesizes existing literature to identify how primary care providers are currently managing vaping among young people and highlights gaps in their preparedness to address this growing public health concern.
Evans-Polce Rebecca J, Lim Chaewon, Smith Danielle M et al.. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2026 May. doi:10.1093/ntr/ntag108
Summary
This research examined how US youth transition between different nicotine use patterns (vaping only, dual use with cigarettes, or switching away from vaping) and whether these transitions relate to how often they use e-cigarettes, their level of nicotine dependence, and measurable nicotine exposure in their bodies. Understanding these usage patterns and dependencies can help public health practitioners identify youth at highest risk for sustained nicotine addiction and inform targeted intervention strategies.
Chen Yu, Wang Yan, Li Zhangyan et al.. Tobacco induced diseases. 2026. doi:10.1037/a0019330
Summary
Female Chinese Indonesian college students studying in China use e-cigarettes within a unique context shaped by cultural adaptation and exposure to different regulatory environments between their home and host countries. The study employed qualitative interviews to understand how acculturation processes influence e-cigarette adoption and use patterns among this international student population, revealing how cultural, social, and environmental factors intersect to shape vaping behaviors.
Phetphum Chakkraphan, Prajongjeep Atchara, Keeratisiroj Orawan et al.. Public health. 2026 May. doi:10.1016/j.puhe.2026.106334
Summary
Secondary school students in Thailand who use e-cigarettes showed increased cannabis use and susceptibility to cannabis use. The study highlights a concerning association between vaping and cannabis use among Thai adolescents, suggesting that e-cigarette use may be part of a broader pattern of substance use among youth in this population.
Hébert Emily T, Bataineh Bara S, Marti C Nathan et al.. Substance use & misuse. 2026 May. doi:10.1080/10826084.2026.2670609
Summary
Social media exposure to vaping-related content—including both industry advertising and user-generated posts—is associated with increased e-cigarette use among Mexican American college students. This relationship appears particularly important for understanding vaping trends in this vulnerable population, where social media normalization of e-cigarette use may influence adoption and regular use patterns.
Epidemiology—Disparities
Amos Natalie, Anderson Joel, Grant Ruby et al.. Archives of sexual behavior. 2026 May. doi:10.1080/14681994.2017.1419570
Summary
This research examined how smoking and alcohol use patterns differ among bisexual+ (Bi+) cisgender people depending on whether they are in same-gender or opposite-gender relationships. The study highlights that Bi+ individuals face distinct health risks and stressors based on their relationship configuration, with those in same-gender partnerships potentially experiencing anti-LGBTQA+ discrimination while those in opposite-gender relationships may face different social pressures, suggesting the need for tailored public health approaches for this population.
Adjei Naomi, Lewinson Terri, Dasgupta Abhirupa et al.. Frontiers in public health. 2026. doi:10.1080/19485565.2023.2260742
Summary
Extended-stay hotel residents in Atlanta experience high rates of loneliness and smoking, reflecting broader vulnerabilities among low-income populations lacking stable housing. Understanding the connection between housing instability, social isolation, and tobacco use can help public health programs better reach and support this underserved population.
Heng Pei Pei, Saminathan Thamil Arasu, Robert Lourdes Tania Gayle et al.. Tobacco induced diseases. 2026. doi:10.1002/14651858.CD003999.pub5
Summary
Malaysian researchers examined how quickly smokers have their first cigarette after waking as a measure of nicotine dependence severity and its relationship to sustained tobacco use. Time to first cigarette is an established behavioral indicator that helps identify smokers with higher dependence levels who face greater challenges in quitting successfully.
Karam David, Haddad Chadia, Sacre Hala et al.. Archives of public health = Archives belges de sante publique. 2026 May. doi:10.1186/s13690-026-01934-y
🍁 Canadian 🔓 Open Access
Summary
Researchers examined whether self-reported smoking rates in Lebanon accurately reflect actual tobacco dependence, particularly among women and youth where social desirability bias may affect honest reporting. The study highlights that perceived smoking prevalence may significantly underestimate actual dependence in culturally sensitive populations, suggesting that public health surveillance and intervention strategies need to account for reporting differences across demographic groups.
Epidemiology—Prevalence
Krasanakis Theodoros, Bouloukaki Izolde, Christodoulakis Antonios et al.. Substance use & addiction journal. 2026 May. doi:10.1177/29767342261446843
Summary
The FRESHAIR4Life study examined both internal factors (such as personality traits and psychological characteristics) and external factors (such as peer influence, family dynamics, and socioeconomic conditions) that contribute to smoking behavior among adolescents in Crete, Greece. Understanding these multiple influences on adolescent smoking can help public health practitioners develop more comprehensive prevention and intervention strategies tailored to the specific contexts and risk factors affecting youth in this population.
Iliyasu Zubairu, Abdullahi Hadiza M, Kerter Shima et al.. BMJ public health. 2026. doi:10.1093/her/cyaf057
Summary
A mixed-methods study examined waterpipe tobacco use among university students in Northern Nigeria, investigating how common the practice is, what risks students perceive, and why they choose to use it. Understanding these patterns and motivations is critical for developing targeted public health strategies to address the growing use of alternative nicotine delivery methods among young adults in this region.
Rossi Kristen R, Russell Scott J, Mabila Sithembile L. MSMR. 2026 May.
Summary
Researchers assessed tobacco and nicotine use among active U.S. military service members in 2023 by combining health assessment data with medical diagnostic codes to address the challenge of accurately measuring smoking patterns in this population. The study highlights the importance of using multiple data sources to capture tobacco use prevalence among military personnel, a group at elevated risk for smoking-related health consequences.
Silva Júnior João Ferreira, Gonçalves Filho Antônio, Carneiro Verônica Silva. Cadernos de saude publica. 2026. doi:10.1101/2025.02.14.25322276v1
Summary
A Brazilian national survey tracked electronic nicotine delivery systems (ENDS) use between 2019 and 2023 to understand how common vaping is and who uses these products. The research found that ENDS use has been increasing in Brazil despite the country's strong tobacco control policies, with important variations across different population groups that public health programs should consider.
Damasceno-de-Freitas Hannae Coelho, Pontes-Silva André, Marquez-de-Souza Renata Nogueira Duran et al.. Sao Paulo medical journal = Revista paulista de medicina. 2026. doi:10.1016/j.puhe.2024.09.025
Summary
This national cross-sectional study examined e-cigarette use patterns among 16,093 Brazilian adults using 2023 Vigitel surveillance data, analyzing how prevalence varies across sociodemographic and geographic groups. The research provides current estimates of e-cigarette adoption in Brazil and identifies which population subgroups are most likely to use these products, supporting evidence-based tobacco monitoring and policy development at national and global levels.
Health Effects—Cancer
Shu Timothy D, Smith Lynette M, Gunnarsson Erik et al.. Pancreatology : official journal of the International Association of Pancreatology (IAP) … [et al.]. 2026 May. doi:10.1016/j.pan.2026.05.004
Summary
Cigarette smoking accelerates the development of pancreatic cancer in individuals carrying genetic mutations that increase susceptibility to this disease. This finding suggests that people with hereditary pancreatic cancer risk factors face an even greater health threat from smoking than the general population, highlighting the importance of smoking cessation support for this high-risk group.
Yan Xiao, Liao Chenyi, Qian Shuangqiang et al.. International journal of women's health. 2026. doi:10.1007/s13167-021-00241-6
Summary
Researchers examined breast cancer burden in BRICS countries (Brazil, Russia, India, China, South Africa) from 1990-2021 and investigated whether smoking, high alcohol use, high body mass index, and low physical activity actually cause breast cancer using advanced statistical methods. The study combines population-level disease data with causal analysis to explain differences in breast cancer rates across these countries and identify which risk factors have the strongest causal relationships with breast cancer development.
Sorayaie Azar Amir, Wiil Uffe Kock, Henriksen Margrethe Bang Høstgaard et al.. Studies in health technology and informatics. 2026 May. doi:10.3233/SHTI260310
Summary
Researchers developed artificial intelligence models using transformer technology to detect smoking behaviors and lung cancer symptoms from electronic health records in Denmark. The models were designed to improve early detection of lung cancer by simultaneously identifying smoking patterns and related symptoms, which could help identify high-risk individuals for timely clinical intervention.
Aswathi G, Carvalho Andre, Palaniraja Sathishrajaa et al.. BMC public health. 2026 May. doi:10.1186/s12889-026-27796-1
Summary
A systematic review and meta-analysis examined how smoking tobacco and alcohol consumption increase oral cancer risk at different exposure levels. The research quantifies the dose-response relationships for these established risk factors, providing clearer evidence on how much tobacco and alcohol exposure corresponds to increased cancer risk. These findings can inform public health messaging and clinical guidance about the combined dangers of tobacco and alcohol use for oral health.
Yang Shasha, Dai Ziyu, Yang Baishuang et al.. Ecotoxicology and environmental safety. 2026 May. doi:10.1016/j.ecoenv.2026.120288
Summary
Cigarette smoke damages the cells lining blood vessels in the lungs, creating an environment that promotes the spread of lung adenocarcinoma tumors. The study identified a specific molecular pathway (BMP4-Smad1/5/9-ID1 axis) through which smoke-induced vascular damage facilitates cancer metastasis, suggesting that smoking's harmful effects extend beyond direct damage to cancer cells themselves to reshape the surrounding tissue environment in ways that accelerate cancer progression.
Li Zihan, Xie Boxuan, Liu Xilei et al.. Chemical research in toxicology. 2026 May. doi:10.1021/acs.chemrestox.5c00464
Summary
Researchers investigated how nicotine from cigarette smoke promotes the progression of lung cancer at the cellular level, specifically examining the molecular pathways involved in nonsmall cell lung cancer (A549) cells. The study focused on understanding the mechanisms by which nicotine activates certain receptors and signaling pathways that drive cancer cell growth and spread, providing insight into why tobacco consumption remains a leading cause of cancer worldwide.
Ruan Liancheng, Wu Han, Cai Yanli. Medicine. 2026 May. doi:10.1097/MD.0000000000048844
Summary
Researchers used genetic analysis methods to investigate how smoking intensity increases lung cancer risk, finding that this relationship may be mediated through changes in blood lipid profiles, specifically sphingomyelin and phosphatidylcholine. The study provides evidence for a biological pathway linking daily smoking to lung cancer development, suggesting that the harmful effects of smoking intensity work partly through alterations in lipid metabolism.
Health Effects—Cardiovascular
Nebbioso Marcella, Calzolaio Francesca, Castellani Valentina et al.. Toxicology mechanisms and methods. 2026 May. doi:10.1080/15376516.2026.2678476
Summary
Researchers examined whether heated tobacco products (HTPs)—devices that heat rather than burn tobacco—affect blood flow in the eye's choriocapillaris, a layer of tiny blood vessels critical for vision. The study compared smokers who had never used HTPs to understand how these newer tobacco products might impact vascular health, contributing to the limited evidence base on HTP safety.
Brath Helmut, Huber Simone, Parzer Verena et al.. Wiener klinische Wochenschrift. 2026 May. doi:10.1016/j.vaccine.2017.07.064
Summary
Smoking and secondhand smoke exposure significantly increase both the development of diabetes and the risk of serious diabetes complications. While quitting smoking may lead to some weight gain and temporary increase in diabetes risk, the cardiovascular and overall health benefits of cessation substantially outweigh these concerns, resulting in reduced heart disease and premature death.
Lenich Ann-Kathrin, Litz Angela, Reindl Lisa-Marie et al.. Archives of toxicology. 2026 May. doi:10.1007/s40262-015-0337-4
Summary
Current clinical practice records smoking status as a simple yes/no question, but this oversimplifies the reality of tobacco use and may miss important drug interactions. Cigarette smoke is known to affect how the body processes many medications through changes in liver enzymes (CYP450), yet the effects of other tobacco products like e-cigarettes and smokeless tobacco on these same drug-processing systems remain unclear. The research recommends that healthcare providers adopt more detailed tobacco use assessments to improve medication safety and effectiveness.
Park Ji Hyeon, Lee Yoo Jeong, Hwang In Cheol et al.. Journal of the College of Physicians and Surgeons–Pakistan : JCPSP. 2026 May. doi:10.29271/jcpsp.2026.05.680
Summary
Among non-diabetic smokers in Korea, nicotine dependence was independently associated with worse glycaemic control, as measured by fasting glucose and glycated hemoglobin levels. This finding suggests that nicotine dependence may be a prognostic factor for developing metabolic dysfunction and diabetes risk, even in people without existing diabetes.
Ashraf Nasir, abuZarifa Maha, Ashraf Yasir et al.. Journal of the College of Physicians and Surgeons–Pakistan : JCPSP. 2026 May. doi:10.29271/jcpsp.2026.05.674
Summary
This cross-sectional study examined how cigarette smoking affects cholesterol and other blood lipids in men aged 20-60 years. The research compared lipid profiles between male smokers and non-smokers to determine whether smoking negatively impacts cardiovascular risk factors through changes in blood lipid levels.
Knoedler Leonard, Hoch Cosima C, Schaschinger Thomas et al.. Journal of stomatology, oral and maxillofacial surgery. 2026 May. doi:10.1016/j.jormas.2026.102842
Summary
Researchers examined whether nicotine use negatively affects surgical outcomes in patients undergoing fibula free flap reconstruction, a common procedure for jaw and facial reconstruction after cancer or trauma. The study used a large surgical database to compare 30-day complications and outcomes between patients who used nicotine and those who did not, contributing to evidence on smoking's impact on surgical recovery and wound healing.
Health Effects—Mental Health
Liu Yi, Wei Hao, Zhang Jing et al.. Chemico-biological interactions. 2026 May. doi:10.1016/j.cbi.2026.112148
Summary
This research examines how nicotine interacts with nicotinic acetylcholine receptors in the brain to produce rewarding effects that reinforce tobacco use and addiction. Understanding these neurobiological mechanisms provides insights into why nicotine is so addictive and how it maintains dependence behaviors in tobacco users.
Kwon Elizabeth, Adekunle Damilola, Lin Hsien-Chang et al.. Child abuse & neglect. 2026 May. doi:10.1016/j.chiabu.2026.108136
Summary
This longitudinal study examined how different types of childhood adversity (threat-based experiences like violence versus deprivation-based experiences like poverty) distinctly affect adolescent smoking, drinking, and depression outcomes. The research moves beyond simply counting total adverse experiences to understand how the specific nature, timing, and duration of childhood hardships may differentially impact youth substance use and mental health vulnerabilities.
Chen Hui, Wang Jingjing, Lai Sirui et al.. Neurology. 2026 Jun. doi:10.1212/WNL.0000000000218123
Summary
A prospective cohort study examined whether smoking cessation affects dementia risk and whether weight gain after quitting smoking influences this relationship. The research helps clarify the long-term neurological benefits of quitting smoking, an important consideration for smokers concerned about health trade-offs when they stop smoking.
Hu Junwen, Li Zezhi. Current neuropharmacology. 2026 May. doi:10.2174/011570159X433380260309071659
Summary
People with schizophrenia smoke at significantly higher rates than the general population. This review examines how nicotine affects brain chemistry in schizophrenia, particularly through its interaction with nicotinic acetylcholine receptors and its effects on dopamine and glutamate neurotransmission, to explain both why individuals with schizophrenia are drawn to smoking and how it may influence their symptoms.
Chen Xuyu. Annals of general psychiatry. 2026 May. doi:10.1186/s12991-026-00675-0
Summary
Researchers examined how smoking and depressive symptoms are connected by studying whether systemic inflammation (the body's inflammatory response) acts as a biological link between these two conditions in a nationally representative US sample. Understanding this inflammation mechanism could help explain why smokers experience higher rates of depression and may inform future mental health interventions for smoking populations.
Durazzo Timothy C, Carolan Riley E, Beauregard Lauren H et al.. Drug and alcohol dependence. 2026 May. doi:10.1016/j.drugalcdep.2026.113194
Summary
Researchers examined brain metabolite levels in people receiving treatment for alcohol use disorder, comparing those who smoke cigarettes to non-smokers. Cigarette smoking, along with a history of major depression and PTSD diagnosis, were associated with altered metabolite levels in a brain region (left dorsolateral prefrontal cortex) important for decision-making and impulse control, suggesting smoking may have additional neurobiological effects in this vulnerable population.
Soares Érica Novaes, Bartolomeo Cynthia Silva, Nicoliche Tiago et al.. Research square. 2026 May. doi:10.21203/rs.3.rs-9410157/v1
Summary
Researchers investigated how nicotine affects astrocytes (brain support cells) that contain alpha-synuclein, a protein associated with Parkinson's disease. The study found that nicotine protected these cells from damage caused by aminochrome, a toxic byproduct of dopamine breakdown that can trigger harmful protein clumping and cell death. These findings suggest a potential neuroprotective mechanism of nicotine in Parkinson's disease, though the incomplete abstract limits full interpretation of the results.
Hu Xinhui, Li Guihua, Dai Kangle et al.. Tobacco induced diseases. 2026. doi:10.1186/s13561-023-00435-w
Summary
Researchers analyzed global data from 1990-2021 to quantify how much dementia burden among adults aged 40+ years is attributable to smoking, with projections through 2035. The study examines smoking as a modifiable risk factor for dementia and tracks long-term trends in smoking-related dementia cases despite improvements in healthcare and reductions in overall dementia prevalence and mortality.
Health Effects—Other
Imène Kacem, Asma Chouchane, Mounira Ben Yahia et al.. Frontiers in allergy. 2026. doi:10.1111/j.0105-1873.2006.00871.x
Summary
This cross-sectional study examined the relationship between tobacco smoking and the severity of hand eczema, a common occupational skin condition, in a North African adult population. The research investigated whether smoking influences how severe hand eczema becomes, addressing a gap in the scientific literature where this particular association has not been extensively studied.
Haneberg Erik, Harkin William, Singh Harmanjeet et al.. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. 2026 May. doi:10.1002/arj.70328
Summary
Researchers identified smoking as one of several risk factors associated with postoperative shoulder stiffness requiring additional surgery following arthroscopic rotator cuff repair. The study examined patient characteristics and medical history between 2005 and 2021 to determine which factors increased the likelihood of developing stiffness complications after this common shoulder surgery.
Health Effects—Pregnancy/Perinatal
Zhang Min Jin, Wang Long, Ding Sijing et al.. BMC public health. 2026 May. doi:10.1186/s12889-026-27789-0
Summary
Reproductive-aged Chinese women exposed to secondhand smoke from their husbands' smoking have an increased risk of developing impaired fasting glucose and diabetes. This finding highlights the importance of reducing secondhand smoke exposure in households as a maternal and child health strategy, particularly among women of childbearing age.
Johnstone Samantha, Schenkel Ashley, Canazzi Samantha et al.. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2026 May. doi:10.1093/ntr/ntag118
Summary
A systematic review and meta-analysis examined birth outcomes in pregnancies exposed to electronic nicotine delivery systems (e-cigarettes/vaping). Despite ENDS being promoted for smoking cessation during pregnancy, this review synthesizes evidence on their actual effects on newborn health outcomes to clarify whether they represent a safer alternative to conventional cigarettes for pregnant individuals.
Bellieni Carlo Valerio. Journal of medical ethics. 2026 May. doi:10.1136/jme-2026-112087
Summary
Research demonstrates that fetuses and newborns experience pain responses similar to adults starting at 20-22 weeks of gestation, based on electrophysiological, chemical, and behavioral evidence. This finding has implications for understanding fetal and neonatal responses to harmful exposures during pregnancy, including tobacco smoke, which can affect fetal development and pain perception.
Health Effects—Respiratory
Has-Elci Hande, Taş Duygu, Güney Zeliha et al.. Journal of periodontology. 2026 May. doi:10.1002/jper.70145
Summary
Smoking negatively affects the healing of gum tissue following a common periodontal surgical procedure (coronally advanced flap with connective tissue graft). This prospective study compared healing outcomes between smokers and non-smokers over a 3-12 month period, demonstrating that smoking impairs the body's ability to recover and achieve successful root coverage after periodontal treatment.
Oner Fatma, Soysal Fatma, Gokmenoglu Ceren et al.. Oral diseases. 2026 May. doi:10.1111/odi.70371
Summary
Smoking impairs the body's natural defense mechanisms against harmful molecules called reactive oxygen species, which contribute to gum disease (periodontitis). This study examined how smoking affects specific proteins (FoxO-1 and MMP-9) that regulate antioxidant protection and tissue breakdown in the gums, helping explain the biological mechanisms linking smoking to periodontal disease.
Li Xiao, Tian Yushan, Wu Yujuan et al.. Ecotoxicology and environmental safety. 2026 May. doi:10.1016/j.ecoenv.2026.120306
Summary
Researchers used human airway organoids (miniature lung-like structures grown from human stem cells) to test the toxic effects of heated tobacco products and compare them to traditional cigarettes and e-cigarettes. The study identified product-specific toxicity patterns, suggesting that different heated tobacco products have distinct harmful effects on respiratory cells, which could inform public health understanding of these emerging products.
Su Yuhe, Cao Jiamin. Frontiers in immunology. 2026. doi:10.1136/bjophthalmol-2020-317091
Summary
Researchers investigated how smoking increases the risk of thyroid eye disease (TED) by examining immune system changes in smokers. The study used national health survey data to identify a potential mechanism where smoking causes overexpression of HLA-DQA1 protein on T cells, which may trigger or worsen thyroid eye disease development. This finding helps explain the biological pathway linking smoking to this autoimmune eye condition.
Tian Xin, Zhang Wen, You Zaichun et al.. Free radical biology & medicine. 2026 May. doi:10.1016/j.freeradbiomed.2026.05.315
Summary
Researchers identified a protective mechanism in airway cells exposed to cigarette smoke involving a protein called Rab26, which prevents a type of cell death known as ferroptosis. By blocking ferroptosis through suppression of mitochondrial damage pathways, Rab26 may help reduce the airway inflammation and structural changes characteristic of COPD, suggesting a potential therapeutic target for cigarette smoke-related lung disease.
Collin Camille, Perney Pascal, Jeanjean Luc et al.. Annales d'endocrinologie. 2026 May. doi:10.1016/j.ando.2026.102578
Summary
This retrospective study of 78 patients examined smoking status and cessation management in people with moderate to severe Graves' orbitopathy, an eye condition associated with thyroid disease. The research highlights smoking as a significant modifiable risk factor for this condition and documents how smoking cessation is being managed in clinical practice for patients with this eye disease.
Junttila Anni, Heikkinen Janne, Kylmäoja Elina et al.. Archives of toxicology. 2026 May. doi:10.3389/fcell.2022.817877
Summary
Researchers examined how nicotine and cigarette smoke exposure damages mesenchymal stromal cells (MSCs), which are critical for tissue repair in the body. High concentrations of nicotine and cigarette smoke extract triggered cell death and stress responses in these cells, providing insight into why tobacco users experience impaired wound healing and connective tissue damage. These findings suggest that direct toxic effects on repair cells may be a key mechanism through which tobacco use compromises tissue healing.
Kawami Masashi, Nakanishi Maya, Furuichi Yuma et al.. Toxicological sciences : an official journal of the Society of Toxicology. 2026 May. doi:10.1093/toxsci/kfag056
Summary
Researchers investigated how cigarette smoke affects PEPT2, a protein transporter in lung cells that plays a role in respiratory defense. The study found that cigarette smoke extract suppresses PEPT2 function through a cellular signaling pathway known as aryl hydrocarbon receptor signaling, which may help explain how smoking damages the lungs' natural protective mechanisms and contributes to chronic respiratory diseases.
Chen Xiao, Wang Dan, Du Jing et al.. Human mutation. 2026. doi:10.3390/ijms23126778
Summary
Researchers investigated how dexmedetomidine, a medication, might protect lung cells from damage caused by cigarette smoke exposure by examining its interaction with a specific microRNA (miR-146a) and a protein called IGSF11. The study used laboratory models of cigarette smoke-induced chronic obstructive pulmonary disease (COPD) to understand the cellular mechanisms involved in this potential protective effect.
Sun Ruoyan, Benowitz Neal L, Hammond David et al.. American journal of preventive medicine. 2026 May. doi:10.1016/j.amepre.2026.108421
🍁 Canadian
Summary
Young adults who both vape and smoke cannabis experience higher rates of respiratory symptoms compared to those using only one method or neither. Using data from a large national study of 5,211 young adults aged 18-24 without prior respiratory issues, researchers found that dual use of cannabis vaping and smoking significantly increased the risk of developing new respiratory symptoms over time.
Indigenous—Tobacco
Rahman Tabassum, Williams Robyn, Davis Katiska et al.. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2026 May. doi:10.1093/ntr/ntag117
🍁 Canadian
Summary
This study examined factors that protect Aboriginal and Torres Strait Islander youth aged 16-24 years from ever starting to smoke, using data from The Next Generation Youth Wellbeing Study. Understanding the characteristics and circumstances of young Indigenous people who never initiate smoking can inform prevention strategies and help explain why smoking rates remain higher in Indigenous communities despite overall declines since 2004.
Policy—Marketing/Advertising
Heo Geon, Kim Doyoon, Kim Yehyun et al.. JMIR public health and surveillance. 2026 May. doi:10.2196/87537
Summary
Researchers examined how tobacco companies in South Korea use flavor cues and visual design elements on cigarette and heated tobacco product packaging to attract consumers, taking advantage of the country's lack of plain packaging requirements. The study found that packaging remains a significant marketing tool, with flavor descriptors and appealing imagery prominently featured to enhance product appeal and influence purchasing decisions.
Cartledge Yianni, Varnava Andrekos. Medical history. 2026 May. doi:10.1017/mdh.2026.10064
Summary
This historical analysis examines how tobacco companies promoted smoking to migrant communities in Australia through newspaper advertisements between 1930 and 1960, while simultaneously comparing these marketing messages with anti-smoking and anti-cancer public health messaging in the same publications. The research reveals the targeted marketing strategies used to reach vulnerable migrant populations during a critical period before widespread tobacco regulation, highlighting how advertising shaped health behaviors in these communities.
Asfar Taghrid, Abrams Ian, Varroney Shannon et al.. BMC public health. 2026 May. doi:10.1186/s12889-026-26775-w
Summary
Researchers used a mixed-methods approach to evaluate and improve pictorial warning labels (PWLs) for electronic cigarettes, specifically tailored for young adults in the United States. The study addresses a critical gap in tobacco control, as while PWLs are known to be effective in communicating health risks, current designs may not resonate with young e-cigarette users who are targeted by marketing emphasizing product design and nicotine addiction.
Policy—Regulation
Hatsukami Dorothy, Jensen Joni, Reisinger Sarah et al.. Tobacco control. 2026 May. doi:10.1136/tc-2025-059771
Summary
A randomised clinical trial examined how banning ventilated cigarette filters—which create the false impression of reduced harm—might affect smoking behaviour and exposure to toxic smoke chemicals. The study compared smoking patterns and biomarkers of smoke exposure between people who smoked unventilated versus ventilated filtered cigarettes to inform potential regulatory decisions about filter ventilation.
Protection—Secondhand/Thirdhand Smoke
Huang Chen, Li Jiayi, Li RuiCen et al.. BMC pulmonary medicine. 2026 May. doi:10.1186/s12890-026-04353-5
Summary
Researchers developed a non-invasive breath test using proton transfer reaction time-of-flight mass spectrometry to detect tobacco smoke exposure, including secondhand smoke. This method offers a potential alternative to traditional invasive biomarker tests and self-reporting for assessing smoking and passive smoke exposure, which could improve accuracy in identifying exposure among non-smokers and smokers alike.
Hazar Bodrumlu Ebru, Avşar Aysun, Kaplan Elif Buse et al.. BMC medical education. 2026 May. doi:10.1186/s12909-026-09401-6
Summary
Dental students' knowledge and attitudes about secondhand smoke (SHS) exposure and its effects on oral health were assessed to understand their potential role in household-level tobacco prevention. Given that dentists regularly interact with children and families, their adequate understanding of SHS risks is critical for providing effective tobacco prevention counseling and guidance to patients.
Other / Uncategorized
Li Dan, Qi Xinyu, Zhang Zeying et al.. Journal of hazardous materials. 2026 May. doi:10.1016/j.jhazmat.2026.142503
Summary
Researchers engineered a safe strain of Bacillus subtilis bacteria to break down nicotine in the environment and potentially within the human body. This biotechnology approach could offer a new strategy for nicotine remediation and detoxification, addressing nicotine exposure through microbial intervention rather than traditional public health methods.
Zhang Jian, Chen Chong, Hu Yang et al.. Frontiers in bioengineering and biotechnology. 2026. doi:10.3389/fmicb.2022.911791
Summary
This research examines how specific microorganisms and fermented citrus ingredients affect flavor development during cigar fermentation through advanced microbial analysis. The study uses multi-omics approaches to understand the interactions between microbes and flavor compounds, with potential applications for enhancing cigar product characteristics. While focused on fermentation science rather than public health outcomes, the findings may be relevant to understanding tobacco product development and composition.
Zhang Jian, Ren Yinfeng, Jia Yun et al.. Frontiers in microbiology. 2026. doi:10.1016/j.foodchem.2012.07.041
Summary
This research examined how flavonoid compounds from tangerine peel affect the fermentation process of cigar tobacco, including changes to flavor compounds and the microorganisms involved in fermentation. The study used advanced analytical techniques to understand how three main flavonoids (nobiletin, tangeretin, and hesperidin) influence tobacco quality during fermentation. While the research focuses on tobacco product manufacturing rather than public health outcomes, it may have indirect relevance to understanding tobacco product characteristics.
Perkins-McVey Matthew. British journal for the history of science. 2026 May. doi:10.1017/S0007087426102039
Summary
This historical analysis examines how European medical professionals in the nineteenth century responded to Chinese opium smoking practices, leading to European interest in opium vapor therapy. The article explores how knowledge about opium use circulated between colonial contexts and European scientific communities, revealing the complex relationship between colonial encounters and the development of medical treatments in Europe.
Das Nandan, Maiti Bibekananda, De Kalyan et al.. Marine pollution bulletin. 2026 May. doi:10.1016/j.marpolbul.2026.119889
Summary
Cigarette butts are a widespread form of litter in coastal environments that contain toxic chemicals and cellulose acetate filters, which persist in the environment and accumulate over time. The study examines how improperly discarded cigarette butts and their associated trace metals impact beach ecosystems and highlights the need for improved management strategies to address this environmental sustainability challenge.
Schwabe Benjamin T W, Angstman Isabelle M, Vollheyde Katharina et al.. Nature communications. 2026 May. doi:10.1038/s41597-024-02965-2
Summary
Researchers identified the final missing steps in how tobacco plants produce nicotine through an enzymatic process involving glucosylation (sugar attachment), completing the understanding of nicotine biosynthesis. This fundamental biochemistry research clarifies the natural production pathway of nicotine in tobacco plants and may have implications for understanding how plants defend against herbivores.
Tanas Yousef, Harris Peyton, Chen Stephen et al.. Plastic and reconstructive surgery. Global open. 2026 May. doi:10.1097/GOX.0000000000007725
Summary
A study of over 56,000 breast reconstruction patients compared surgical outcomes between those with nicotine dependence and those without. The research examined whether nicotine dependence increased risks of capsular contracture (scar tissue hardening around implants) and other implant-related complications following breast reconstruction surgery.
News Articles 15

Recent tobacco and vaping coverage from news sources.

▶ Browse 15 news articles
RFK Jr. spokesman resigns over fruit-flavored e-cigarette concerns, letter saysAbcnews.com2026-05-14

Richard Danker said the vape authorization "undermines" the department's recent guidance document related to youth risks of flavored nicotine, according to the letter.…
The End of Cigarettes Is ComingThe Atlantic2026-05-04

The U.K. is phasing out smoking. How long will Americans tolerate tobacco—and other vices?…
The Trump administration is bringing back flavored vapes. Advocates and lawmakers say the risks outweigh the benefitsScientific American2026-05-06

The president had vowed to 'save vaping' on the campaign trail in 2024, but the decision is already drawing fire from anti-nicotine advocates and a bipartisan group of lawmakers…
Scientists solve 200-year-old puzzle of how tobacco plants make nicotineYork.ac.uk2026-05-22

Scientists have uncovered how tobacco plants naturally make nicotine, solving a mystery that has puzzled researchers for nearly two centuries.…
‘Smoke Weed and Earn Bitcoin’ with This Vape Pen in Our Increasingly Dystopian NightmareGizmodo.com2026-05-17

Should we really be adding gamification features to getting high?…
E-Cigarettes Can Help You Quit Smoking Says New StudyForbes2026-05-20

E-cigarettes containing nicotine can help people quit smoking according to a new study and may be more helpful for some smokers than other nicotine products like patches.…
Second Trump Administration’s Pivot On Vaping Leads To ResignationsForbes2026-05-15

High level resignations in protest against the push to allow sales of fruit-flavored vapes suggest a break in policy between the first and second Trump administrations.…
Study: Regular Exercise Linked to Higher Smoking Cessation RatesNaturalnews.com2026-05-14

A growing body of evidence indicates that regular physical activity may improve the likelihood of quitting smoking. According to a study published in the Oxford journal Nicotine & …
'Big AI' is subverting regulations just like tobacco and oil firmsTheregister.com2026-05-18

Researchers warn that regulatory capture means industry concerns trump those of citizens…
Pay To Vape: Big Tobacco's Brazen Trump PAC BetCrooksandliars.com2026-05-23

It was already known that President Donald Trump pressured top health officials to allow flavored vapes to hit the market after being leaned on by Big Tobacco executives earlier th…
Trump’s FDA Commissioner Marty Makary resignsScientific American2026-05-12

Makary, a face of Trump’s Make America Healthy Again agenda, oversaw the embattled agency as it dealt with vaping, abortion and other issues…
Smoke 'em if you've got 'em: Florida's Ron DeSantis celebrates cigarsUSA Today2026-05-15

Florida Gov. Ron DeSantis is featured on the cover of Cigar Aficionado.…
WATCH: California fire crews save Little League game from power outageAbcnews.com2026-05-17

The Lakeside fire department, responding to check on the smoking power lines causing the outage, decided to help save the game with lighting from a new rescue unit.…
Zyn Isn’t SinDaily Signal2026-05-03

Zyns are super popular. They are little pouches people tuck into their lips to get a hit of nicotine. Zyn has competitors, like Velo and On!, but Zyn has most of the market. Young …
Ontario Tobacco Research Unit
Current Abstracts is a monthly research digest produced by OTRU  ·  otru.org
Automated literature search via PubMed  ·  AI-assisted categorization and summarization  ·  Hot Topics identified via Reddit community engagement  ·  Editorial review recommended before publication.

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